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Dementia With Lew Body: Impacts of Surgery
Journal article   Open access   Peer reviewed

Dementia With Lew Body: Impacts of Surgery

Farzana Pervin, Carolyn Edwards and Carol F Lippa
American journal of Alzheimer's disease and other dementias, v 31(1)
Feb 2016
PMID: 26006790
url
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852939View
Published, Version of Record (VoR)Open Access (License Unspecified) Open

Abstract

Alzheimer Disease - physiopathology Anesthetics - adverse effects Cognition Disorders - etiology Delirium - etiology Dementia - pathology Female Humans Lewy Body Disease - genetics Lewy Body Disease - physiopathology Male Postoperative Complications - psychology Surgical Procedures, Operative
Patients who have dementia with Lewy bodies (DLB) and undergo surgery may develop aggravated postoperative cognitive dysfunction or postoperative delirium. Many patients with DLB respond poorly to surgery and anesthesia, and their conditions may worsen if they have other medical complications along with dementia. They may also face high risk of prolonged hospital stay, increased medical problems and/or mortality, causing significant physical, psychosocial, and financial burdens on individuals, family members, and society. Anesthesia, pain medications, old age, and surgery-related stresses are usually held responsible for the complications; however, the exact causes are still not fully understood. Literature on surgery-related complications for patients with DLB appears to be inadequate, and hence the topic merits detailed and systematic research. This article reviews postoperative complications and various surgery-related risk factors for DLB in light of other dementias such as Alzheimer's disease, as their neuropathologic features overlap with those of DLB.

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Web of Science research areas
Clinical Neurology
Geriatrics & Gerontology
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