Journal article
Detection of Organophosphates Using an Acetyl Cholinesterase (AChE) Coated Microcantilever
Instrumentation science & technology, v 32(2), pp 175-183
27 Dec 2004
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Abstract
A microcantilever modified with a layer of acetyl cholinesterase (AChE) responding to paraoxon is reported in this work. Acetyl cholinesterase was immobilized on a microcantilever through a cross linker to a monolayer on gold surface of the microcantilever. The microcantilever underwent a maximum of 7 nm bending due to the inhibition of AChE by paraoxon that slightly changed the conformation of AChE.
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Details
- Title
- Detection of Organophosphates Using an Acetyl Cholinesterase (AChE) Coated Microcantilever
- Creators
- Xiaodong Yan - Louisiana Tech UniversityYanjun Tang - Louisiana Tech UniversityHaifeng Ji - Louisiana Tech UniversityYuri Lvov - Louisiana Tech UniversityThomas Thundat - Oak Ridge National Laboratory
- Publication Details
- Instrumentation science & technology, v 32(2), pp 175-183
- Publisher
- Taylor & Francis Group
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemistry
- Web of Science ID
- WOS:000222250000007
- Scopus ID
- 2-s2.0-1842480182
- Other Identifier
- 991019335222104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Chemistry, Analytical
- Instruments & Instrumentation