Journal article
Determinants of Operative Survival Following Combined Mitral Valve Replacement and Coronary Revascularization
The Annals of thoracic surgery, v 34(5), pp 482-489
Nov 1982
PMID: 6982691
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To determine the operative survival rate following combined mitral valve replacement (MVR) and coronary artery bypass graft (CABG) operation, we evaluated 100 patients, who were seen consecutively at the Peter Bent Brigham and Brigham and Women's Hospital from 1972 to 1981. There were 63 men and 37 women; the mean age was 62 years. Thirty-six patients were in New York Heart Association (NYHA) Functional Class III, and 64 were in Functional Class IV. Mitral regurgitation was predominant in 76 patients; mitral stenosis, in 24. Emergency operations were performed in 15 patients, and elective or semielective operations were performed in 85.
There were 18 operative deaths (18%): 9 in patients having elective operations (10.5%) and 9 in those having emergency operations (60%;
p < 0.01). Significant preoperative factors related to operative death were NYHA functional class, increased pulmonary vascular resistance, lower cardiac index, and lower ejection fraction in the nonsurvivors. The rate of survival did not differ according to sex, age, or degree of coronary artery disease. In addition, myocardial protection with potassium cardioplegia and complete coronary revascularization significantly reduced operative mortality in the elective group of patients but did not alter the mortality in the emergency group.
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Details
- Title
- Determinants of Operative Survival Following Combined Mitral Valve Replacement and Coronary Revascularization
- Creators
- Verdi J. DiSesaLawrence H. CohnJohn J. CollinsJ. Kenneth KosterStephen VanDevanter
- Publication Details
- The Annals of thoracic surgery, v 34(5), pp 482-489
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:A1982PP68000002
- Scopus ID
- 2-s2.0-0020469627
- Other Identifier
- 991021463597604721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Respiratory System
- Surgery