Journal article
Determination of octanol–water partition coefficients of pesticides by microemulsion electrokinetic chromatography
Journal of Chromatography A, v 930(1), pp 145-154
2001
PMID: 11681572
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Microemulsion electrokinetic chromatography (MEEKC) was evaluated as a screening tool for the indirect measurement of octanol–water partition coefficients (log
P
o/w) of pesticide compounds. Over 80 pesticide compounds representing a variety of structural characteristics were studied, and good correlation of log
P
o/w with the logarithm of the retention factor was found. The microemulsion system studied allowed the separation of compounds in the log
P
o/w range of −1 to 7. In addition, a smaller set of simple organic molecules that vary in structural features was evaluated and compared to the pesticide log
P
o/w calibration. The pesticide and simple organic molecule log
P
o/w calibration lines were statistically similar. This suggests that a universal set of standard compounds may be employed for the log
P
o/w calibration to provide measurements for a variety of compounds with good accuracy.
Metrics
Details
- Title
- Determination of octanol–water partition coefficients of pesticides by microemulsion electrokinetic chromatography
- Creators
- W.L Klotz - Department of Chemistry, Villanova University, Villanova, PA 19085, USAM.R Schure - Analytical and Computational Technology Center, Rohm and Haas Company, Spring House, PA 19477-0904, USAJ.P Foley - Department of Chemistry, Drexel University, Philadelphia, PA 19104, USA
- Publication Details
- Journal of Chromatography A, v 930(1), pp 145-154
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemistry
- Web of Science ID
- WOS:000171510200015
- Scopus ID
- 2-s2.0-0035964891
- Other Identifier
- 991014878172504721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Biochemical Research Methods
- Chemistry, Analytical