Journal article
Development of a Finite Element Model of the Pediatric Thoracic and Lumbar Spine, Ribcage, and Pelvis With Orthotropic Region-Specific Vertebral Growth
Journal of biomechanical engineering, v 144(10)
01 Oct 2022
PMID: 35466381
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Finite element (FE) modeling of the spine has increasingly been applied in orthopedic precision-medicine approaches. Previously published FE models of the pediatric spine growth have made simplifications in the geometry of anatomical structures, material properties, and representation of vertebral growth. To address those limitations, a comprehensive FE model of a pediatric (10-year-old) osteo-ligamentous thoracic and lumbar spine (T1-L5 with intervertebral discs (IVDs) and ligaments), ribcage, and pelvis with age- and level-specific ligament properties and orthotropic region-specific vertebral growth was developed and validated. Range of motion (ROM) measures, namely, lateral bending, flexion-extension, and axial rotation, of the current 10 YO FE model were generally within reported ranges of scaled in vitro adult ROM data. Changes in T1-L5 spine height, as well as kyphosis (T2-T12) and lordosis (L1-L5), angles in the current FE model for two years of growth (from ages 10 to 12 years) were within ranges reported from corresponding pediatric clinical data. The use of such comprehensive pediatric FE models can provide clinically relevant insights into normative and pathological biomechanical responses of the spine, and also contribute to the development and optimization of clinical interventions for spine deformities.
Metrics
Details
- Title
- Development of a Finite Element Model of the Pediatric Thoracic and Lumbar Spine, Ribcage, and Pelvis With Orthotropic Region-Specific Vertebral Growth
- Creators
- Sriram Balasubramanian - Drexel UniversityChristian R D'Andrea - Drexel UniversityGirish Viraraghavan - Drexel UniversityPatrick J Cahill - Children's Hospital of Philadelphia
- Publication Details
- Journal of biomechanical engineering, v 144(10)
- Publisher
- ASME
- Grant note
- 174816 / Directorate for Engineering
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000848277700002
- Scopus ID
- 2-s2.0-85130636546
- Other Identifier
- 991019173566104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biophysics
- Engineering, Biomedical