Logo image
Back
Development of a clinically relevant impingement test method for a mobile bearing lumbar total disc replacement
Journal article   Peer reviewed

Development of a clinically relevant impingement test method for a mobile bearing lumbar total disc replacement

Ryan Siskey, Jonathan Peck, Hitesh Mehta, Allison Kosydar, Steven Kurtz and Genevieve Hill
The spine journal, v 16(9), pp 1133-1142
Sep 2016
DOI: https://doi.org/10.1016/j.spinee.2016.05.004
PMID: 27179625
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Cobalt chrome Explant analysis Impingement Retrieval analysis Total disc arthroplasty Total disc replacement Ultra-high molecular weight polyethylene Wear
Total disc arthroplasty is an alternative therapy to spinal fusion for the treatment of neck or low back pain and is hypothesized to reduce the risk of disease progression to the adjacent spinal levels. Radiographic and retrieval analyses of various total disc replacements (TDRs) have shown evidence of impingement damage. Impingement of TDRs can occur when the device reaches the limits of its functional range of motion, causing contact between peripheral regions of the device. Impingement can be associated with increased wear and mechanical damage; however, impingement conditions are not simulated in current standardized mechanical bench test methods. This study explored the test conditions necessary to apply clinically relevant impingement loading to a lumbar TDR in vitro. An experimental protocol was developed and evaluated using in vivo retrievals for qualitative and quantitative validation. Retrieval analysis was conducted on a set of 11 size 3 retrieved Charité devices using American Society for Testing and Materials F561 as a guide. The impingement range of motion was determined using a combination of modeling and experiments, and was used as an input in vitro testing. A 1-million cycle in vitro test was then conducted, and the in vitro samples were characterized using methods similar to the retreived devices. All in vitro tested samples exhibited impingement regions and damage patterns consistent with retrieved devices. Consistent with the retrievals, the impingement damage on the rim was a combination of abrasive wear and plastic deformation. Micro computed tomography (microCT) was used to quantitatively assess rim damage due to impingement. Rim penetration was statistically lower in the retrievals when compared with both in vitro groups. Rim elongation was comparable among all groups. The simulated-facet group had statistically greater angular rim deformations than the retrieval group and the no-facet group. Results demonstrate that clinically relevant impingement seen on mobile bearings of lumbar TDRs can be replicated on the bench.

Metrics

11 Record Views
10 citations in Web of Science
10 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Industry collaboration
Domestic collaboration
Web of Science research areas
Clinical Neurology
Orthopedics
Logo image