Journal article
Development of a dual‐spray electrospray deposition system for matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
Rapid communications in mass spectrometry, v 22(8), pp 1168-1174
30 Apr 2008
PMID: 18338374
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A new method of matrix‐assisted laser desorption/ionization (MALDI) sample preparation using a dual‐spray electrospray deposition system is demonstrated and employed for the investigation of gas‐phase cationization reactions in the MALDI plume. The dual‐spray electrospray system is found to increase the homogeneity of the sample similarly to that of a conventional single‐spray electrospray system. The dual‐spray electrospray system allows for intimate mixing of separately prepared sample components and results in improved quantitative results. The development of this device also leads to the possibility of mixing sample components prepared in different solvents without the need to be concerned with solvent miscibility. Copyright © 2008 John Wiley & Sons, Ltd.
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Details
- Title
- Development of a dual‐spray electrospray deposition system for matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
- Creators
- William J ErbKevin G Owens
- Publication Details
- Rapid communications in mass spectrometry, v 22(8), pp 1168-1174
- Publisher
- John Wiley & Sons, Ltd; Chichester, UK
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemistry
- Web of Science ID
- WOS:000255362300011
- Scopus ID
- 2-s2.0-42649095163
- Other Identifier
- 991014877932004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biochemical Research Methods
- Chemistry, Analytical
- Spectroscopy