Journal article
Development of array piezoelectric fingers towards in vivo breast tumor detection
Review of scientific instruments, v 87(12), pp 124301-124301
Dec 2016
PMID: 28040934
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We have investigated the development of a handheld 4 × 1 piezoelectric finger (PEF) array breast tumor detector system towards
in vivo
patient testing, particularly, on how the duration of the DC applied voltage, the depression depth of the handheld unit, and breast density affect the PEF detection sensitivity on 40 patients. The tests were blinded and carried out in four phases: with DC voltage durations 5, 3, 2, to 0.8 s corresponding to scanning a quadrant, a half, a whole breast, and both breasts within 30 min, respectively. The results showed that PEF detection sensitivity was unaffected by shortening the applied voltage duration from 5 to 0.8 s nor was it affected by increasing the depression depth from 2 to 6 mm. Over the 40 patients, PEF detected 46 of the 48 lesions (46/48)—with the smallest lesion detected being 5 mm in size. Of 28 patients (some have more than one lesion) with mammography records, PEF detected 31/33 of all lesions (94%) and 14/15 of malignant lesions (93%), while mammography detected 30/33 of all lesions (91%) and 12/15 of malignant lesions (80%), indicating that PEF could detect malignant lesions not detectable by mammography without significantly increasing false positives. PEF’s detection sensitivity is also shown to be independent of breast density, suggesting that PEF could be a potential tool for detecting breast cancer in young women and women with dense breasts.
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Details
- Title
- Development of array piezoelectric fingers towards in vivo breast tumor detection
- Creators
- Xin Xu - School of Biomedical Engineering, Science and Health SystemsYoungsoo Chung - School of Biomedical Engineering, Science and Health SystemsAri D Brooks - Department of Surgery, College of MedicineWei-Heng Shih - Department of Materials Science and EngineeringWan Y Shih - School of Biomedical Engineering, Science and Health Systems
- Publication Details
- Review of scientific instruments, v 87(12), pp 124301-124301
- Publisher
- American Institute of Physics
- Grant note
- ;
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems; Materials Science and Engineering; Surgery
- Web of Science ID
- WOS:000392096800041
- Scopus ID
- 2-s2.0-85006046037
- Other Identifier
- 991014877797004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Instruments & Instrumentation
- Physics, Applied