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Development of self‐anchoring bone implants. I. Processing and material characterization
Journal article

Development of self‐anchoring bone implants. I. Processing and material characterization

Abdel Abusafieh, Sorin Siegler and Surya R Kalidindi
Journal of biomedical materials research, v 38(4), pp 314-327
1997
PMID: 9421752

Abstract

bone implants self‐anchoring expansion‐fit mechanism
We recently designed and produced a family of new swelling‐type materials that are potentially capable of self‐fixation in bone. These materials are designed to absorb body fluids and swell by small amounts, which will allow the implants made from these materials to achieve self‐fixation by an expansion‐fit mechanism. The developed material system is essentially a crosslinked random copolymer based on poly(methyl methacrylate‐acrylic acid). For potential structural (load‐bearing) bioimplant applications, we reinforced this copolymer with AS‐4 carbon and Kevlar 49 fibers. The details of processing these materials and the steps involved in optimizing their microstructures are presented in this article. A set of mechanical tests were performed on these materials in both dry and swollen conditions to measure their moduli and yield strengths. In the dry state, the copolymers were found to exhibit Young's moduli in the range of 3 to 4 GPa and yield strengths in the range of 70 to 85 MPa. The reinforced composites exhibited moduli in the range of 15 to 65 GPa and yield strengths in the range of 125 to 500 MPa. Upon controlling the volumetric swelling in these materials to be less than about 10%, the loss in mechanical properties was found to be less than about 30%. These hygromechanical properties are well suited for self‐anchoring bone implant applications. © 1997 John Wiley & Sons, Inc. J Biomed Mater Res (Appl Biomater) 38: 314–327, 1997

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Web of Science research areas
Engineering, Biomedical
Materials Science, Biomaterials
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