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Diabetic ketoacidosis with cerebral hemorrhage and alpha coma in an adolescent female
Journal article   Peer reviewed

Diabetic ketoacidosis with cerebral hemorrhage and alpha coma in an adolescent female

Zohreh Shoar, Christopher Dunne, William Yorns, Francesco De Luca and Geoffrey Rezvani
Journal of pediatric endocrinology & metabolism : JPEM, v 26(5-6), pp 561-564
2013
PMID: 23515102

Abstract

Adolescent Alpha Rhythm Cerebral Hemorrhage - complications Cerebral Hemorrhage - diagnosis Coma - diagnosis Coma - etiology Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - therapy Diabetic Ketoacidosis - complications Diabetic Ketoacidosis - therapy Female Humans Magnetic Resonance Imaging Prognosis Remission Induction
Diabetic ketoacidosis (DKA) is one of the most common and harmful complications of type 1 diabetes in children. The neurologic morbidities, including seizure activity, motor/sensory deficit, and coma, can be seen secondary to cerebral edema, hemorrhage, or ischemia. Alpha-frequency is a normal 8-13 Hz physiologic electroencephalogram rhythm that is seen most prominently in the occipital region of awake people and is augmented by eye closure. In the comatose patient, alpha-rhythm is not usually seen. Alpha-frequency coma (AC) is a rare finding in comatose patients and is generally associated with a poor prognosis. We report an adolescent with severe DKA, intraparenchymal cerebral hemorrhage, and AC, who had a rapid resolution of the neurologic symptoms. Similar to other reported cases, our case suggests that the prognosis for patients with AC may not be always poor when it is associated with DKA.

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Web of Science research areas
Endocrinology & Metabolism
Pediatrics
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