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Diagnosing Autism Spectrum Disorder in Children with Low Mental Age
Journal article   Open access   Peer reviewed

Diagnosing Autism Spectrum Disorder in Children with Low Mental Age

Lauren E Miller, Jeffrey D Burke, Diana L Robins and Deborah A Fein
Journal of autism and developmental disorders, v 49(3), pp 1080-1095
Mar 2019
PMID: 30406437
url
https://doi.org/10.1007/s10803-018-3810-8View
Published, Version of Record (VoR) Open

Abstract

Diagnosis, Differential Age Factors Follow-Up Studies Humans Child, Preschool Infant Male Autism Spectrum Disorder - psychology Algorithms Intelligence - physiology Social Behavior Female Developmental Disabilities - diagnosis Autism Spectrum Disorder - diagnosis Developmental Disabilities - psychology
Autism Spectrum Disorder (ASD) diagnostic tools are not designed for mental ages (MA) below 12 months. Autism Diagnostic Observation Schedule (ADOS) and Childhood Autism Rating Scale (CARS) were examined in 2-year-olds with ASD-low MA (n = 53), Global Developmental Delay (GDD; n = 175), and ASD-higher MA (n = 425). ADOS and CARS demonstrated similar agreement with clinical diagnosis, but ADOS over-classified ASD in low MA, whereas CARS both over- and under-classified. All ADOS items differentiated GDD from ASD. Elementary social behaviors (e.g., eye contact, social interest) were similar across ASD groups, although advanced skills (e.g., pointing, play) were more impaired in ASD-low MA. ASD-low MA, a severe presentation, may require a modified ADOS algorithm to account for developmental delays.

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Collaboration types
Domestic collaboration
Web of Science research areas
Psychology, Developmental
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