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Journal article
Diagnostic accuracy of real‑time point-of-care tracheal ultrasonography for the confirmation of proper endotracheal tube placement in neonatal acute care settings: a systematic review and diagnostic test accuracy meta-analysis
Journal of perinatology : official journal of the California Perinatal Association, v 46, pp 12-18
19 Nov 2025
PMID: 41261147
Featured in Collection : Research Supported by Drexel Libraries' OA Programs
Abstract
Accurate confirmation of endotracheal tube (ETT) placement is critical in neonatal resuscitation. This systematic review and meta-analysis assessed the diagnostic accuracy of point-of-care ultrasound (POCUS) for confirming ETT placement in neonates. We searched PubMed, Scopus, Web of Science, and Cochrane Library through May 2025. Eligible studies included neonates (<28 days) and compared POCUS with gold-standard confirmation (capnography, chest radiography, or direct laryngoscopy). Diagnostic performance was pooled using a bivariate random-effects model. Thirteen studies (930 neonates) met inclusion criteria. POCUS showed pooled sensitivity of 93% and specificity of 59%, with an area under the SROC curve of 92%. tracheal placement was confirmed in 99%, and esophageal misplacement detected in 4%. Subgroup analysis indicated higher accuracy by neonatologists and with linear transducers. POCUS offers a rapid, radiation-free method for confirming neonatal ETT placement. Broader implementation requires standardized techniques and operator training.
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Details
- Title
- Diagnostic accuracy of real‑time point-of-care tracheal ultrasonography for the confirmation of proper endotracheal tube placement in neonatal acute care settings: a systematic review and diagnostic test accuracy meta-analysis
- Creators
- Mohammed Alsabri (Corresponding Author) - Drexel University, College of MedicineEslam Abady - Tanta UniversityMohammed Tarek Hasan - Al-Azhar UniversityShree Rath - All India Institute of Medical Sciences BhubaneswarAhmed Bostamy Elsnhory - Al-Azhar UniversityKhaled Abouelmagd - Al-Azhar UniversityAbdelrahman M. TawfikIbrahim Qattea - Nassau University Medical CenterAysha Hasan - Drexel University, Anesthesiology and Perioperative Medicine
- Publication Details
- Journal of perinatology : official journal of the California Perinatal Association, v 46, pp 12-18
- Publisher
- Springer Nature
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics; College of Medicine; Anesthesiology and Perioperative Medicine
- Web of Science ID
- WOS:001618943200001
- Scopus ID
- 2-s2.0-105022422215
- Other Identifier
- 991022133343204721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Obstetrics & Gynecology
- Pediatrics