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Diastereoselective fluorination of chiral imide enolates using n-fluoro- o-benzenedisulfonimide (nfobs)
Journal article   Peer reviewed

Diastereoselective fluorination of chiral imide enolates using n-fluoro- o-benzenedisulfonimide (nfobs)

Franklin A. Davis and Wei Han
Tetrahedron letters, v 33(9), pp 1153-1156
1992

Abstract

α-Fluoro acids (78–90% ee) and β-fluoro alcohols (89–>95%ee) of well defined stereochemistry are prepared via the diastereoselective fluorination of chiral imide enolates with NFOBS (3). α-Fluoro acids and β-fluoro alcohols of well defined stereochemistry are prepared via the diastereoselective fluorination of chiral imide enolates with N-fluoro- o-benzenedisulfonimide (NFOBS).

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Web of Science research areas
Chemistry, Organic
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