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Diet-induced oxalate nephropathy
Journal article   Open access   Peer reviewed

Diet-induced oxalate nephropathy

Barbara Clark, Mohammad Wisam Baqdunes and Gregory M Kunkel
BMJ case reports, v 12(9), pe231284
Sep 2019
PMID: 31527218
url
https://doi.org/10.1136/bcr-2019-231284View
Published, Version of Record (VoR)CC BY-NC V4.0 Open

Abstract

Oxalate nephropathy is a rare condition and may be overlooked due to lack of recognition and understanding of triggers. An 81-year-old man was sent to nephrologist because of significantly increased creatinine (1.5–1.9 mg/dL) noted for 3 months. He had well-controlled diabetes but no history of kidney disease. He had no chronic diarrhoea or intestinal surgery. He was a health-minded individual who had read extensively about benefit of antioxidants. Initial work-up was unrevealing. Within a few weeks after first visit, he developed acute symptomatic worsening kidney injury with nausea, vomiting and creatinine up to 6.8 mg/dL. Repeat examination of the urine sediment revealed casts containing calcium oxalate crystals. A deeper dietary history revealed widespread oxalate precursor consumption. A kidney biopsy confirmed oxalate nephropathy. Restriction of oxalate consumption combined with adequate hydration, oral calcium acetate resulted in partial renal recovery without need for haemodialysis.

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12 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Urology & Nephrology
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