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Differential reward response to palatable food cues in past and current dieters: a fMRI study
Journal article   Open access   Peer reviewed

Differential reward response to palatable food cues in past and current dieters: a fMRI study

Alice V Ely, Anna Rose Childress, Kanchana Jagannathan and Michael R Lowe
Obesity (Silver Spring, Md.), v 22(5), pp E38-E45
May 2014
DOI: https://doi.org/10.1002/oby.20599
PMID: 23929709
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1002/oby.20599View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze),  Open

Abstract

Body Mass Index Cues Prospective Studies Humans Diet, Reducing - psychology Brain - physiology Energy Intake Neurophysiology Young Adult Magnetic Resonance Imaging Adolescent Diet, Reducing - methods Adult Female Surveys and Questionnaires Feeding Behavior - psychology Taste Reward Meals Weight Gain
Prior neuroimaging research has shown that restrained and unrestrained eaters demonstrate differential brain activation in response to food cues that parallels their food intake in lab studies. These findings were extended by comparing brain activation in response to food cues in normal weight nondieters, historical dieters, and current dieters under the conditions that mimicked past lab studies. Participants (N = 30) were shown pictures of highly and moderately palatable food and neutral cues while being scanned in an fMRI BOLD paradigm following an 8-h fast and again after a liquid meal. In the Fed state, historical dieters showed elevated reward circuitry activation in response to highly palatable food, as compared to nondieters and current dieters. In contrast, current dieters did not show the same pattern of activation as historical dieters, despite their shared history of frequent weight-loss dieting. The parallels between eating behavior and regional brain activation across groups suggest that (1) a neurophysiological response which could represent a vulnerability to overeat exists in some normal weight young women that may increase susceptibility to weight gain in the long term, and (2) current dieting temporarily reverses this vulnerability.

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23 Record Views
25 citations in Web of Science
25 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#5 Gender Equality
#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Endocrinology & Metabolism
Nutrition & Dietetics
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