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Dimensions in cell migration
Journal article   Open access   Peer reviewed

Dimensions in cell migration

Andrew D. Doyle, Ryan J. Petrie, Matthew L. Kutys and Kenneth M. Yamada
Current opinion in cell biology, v 25(5), pp 642-649
01 Oct 2013
PMID: 23850350
url
https://escholarship.org/uc/item/4h14q19cView
Accepted (AM) Open

Abstract

Cell Biology Life Sciences & Biomedicine Science & Technology
The importance of cell migration for both normal physiological functions and disease processes has been clear for the past 50 years. Although investigations of two-dimensional (2D) migration in regular tissue culture have elucidated many important molecular mechanisms, recent evidence suggests that cell migration depends profoundly on the dimensionality of the extracellular matrix (ECM). Here we review a number of evolving concepts revealed when cell migration is examined in different dimensions.

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Cell Biology
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