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Directed ortho metalation - mediated F + introduction. Regiospecific synthesis of fluorinated aromatics
Journal article   Peer reviewed

Directed ortho metalation - mediated F + introduction. Regiospecific synthesis of fluorinated aromatics

Victor Snieckus, Francis Beaulieu, Kunihiko Mohri, Wei Han, Christopher K. Murphy and Franklin A. Davis
Tetrahedron letters, v 35(21), pp 3465-3468
1994

Abstract

Regiospecific fluorination using N-fluorobenzenesulfonimide (NFSi) and N-fluoro- O-benzenedisulfonimide (NFOBS) reagents via directed ortho metalation ( Scheme 1) is reported and exceptions of PhSO 2 transfer from NFSi are described. Graphic

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Chemistry, Organic
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