Logo image
Back
Disability and Recovery of Independent Function in Obstructive Lung Disease: The Cardiovascular Health Study
Journal article   Open access   Peer reviewed

Disability and Recovery of Independent Function in Obstructive Lung Disease: The Cardiovascular Health Study

Vincent S. Fan, Emily R. Locke, Paula Diehr, Anthony Wilsdon, Paul Enright, Sachin Yende, Mark Avdalovic, Graham Barr, Vishesh K. Kapur, Rachel Thomas, …
Respiration, v 88(4), pp 329-338
01 Oct 2014
DOI: https://doi.org/10.1159/000363772
PMID: 25228204
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://www.karger.com/Article/Pdf/363772View
Published, Version of Record (VoR) Open
url
https://doi.org/10.1159/000363772View
Published, Version of Record (VoR) Open

Abstract

Life Sciences & Biomedicine Respiratory System Science & Technology
Background: Chronic obstructive lung disease frequently leads to disability. Older patients may experience transitions between states of disability and independence over time. Objective: To identify factors associated with transition between states of disability and independent function in obstructive lung disease. Methods: We analyzed data on 4,394 participants in the Cardiovascular Health Study who completed prebronchodilator spirometry. We calculated the 1-year probability of developing and resolving impairment in >= 1 instrumental activity of daily living (IADL) or >= 1 activity of daily living (ADL) using transition probability analysis. We identified factors associated with resolving disability using relative risk (RR) regression. Results: The prevalence of IADL impairment was higher with moderate (23.9%) and severe (36.9%) airflow obstruction compared to normal spirometry (22.5%; p < 0.001). Among participants with severe airflow obstruction, 23.5% recovered independence in IADLs and 40.5% recovered independence in ADLs. In the adjusted analyses, airflow obstruction predicted the development of IADL, but not ADL impairment. Participants with severe airflow obstruction were less likely to resolve IADL impairment [RR 0.67 and 95% confidence interval (CI) 0.49-0.94]. Compared to the most active individuals (i.e. who walked >= 28 blocks per week), walking less was associated with a decreased likelihood of resolving IADL impairment (7-27 blocks: RR 0.81 and 95% CI 0.69-0.86 and < 7 blocks: RR 0.73 and 95% CI 0.61-0.86). Increased strength (RR 1.16 and 95% CI 1.05-1.29) was associated with resolving IADL impairment. Conclusions: Disability is common in older people, especially in those with severe airflow obstruction. Increased physical activity and muscle strength are associated with recovery. Research is needed on interventions to improve these factors among patients with obstructive lung disease and disability. (C) 2014 S. Karger AG, Basel

Metrics

7 Record Views
4 citations in Web of Science
4 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
Web of Science research areas
Respiratory System
Logo image