Files and links (1)
Accepted (AM)Open Access (License Unspecified), Open
Journal article
Disruption of the Anterior-Posterior Rotator Cuff Force Balance Alters Joint Function and Leads to Joint Damage in a Rat Model
Journal of orthopaedic research, v 32(5), pp 638-644
01 May 2014
PMID: 24464961
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The rotator cuff assists in shoulder movement and provides dynamic stability to the glenohumeral joint. Specifically, the anterior-posterior (AP) force balance, provided by the subscapularis anteriorly and the infraspinatus and teres minor posteriorly, is critical for joint stability and concentric rotation of the humeral head on the glenoid. However, limited understanding exists of the consequences associated with disruption of the AP force balance (due to tears of both the supraspinatus and infraspinatus tendons) on joint function and joint damage. We investigated the effect of disrupting the APforce balance on joint function and joint damage in an overuse rat model. Twenty-eight rats underwent 4 weeks of overuse to produce a tendinopathic condition and were then randomized into two surgical groups: Detachment of the supraspinatus only or detachment of the supraspinatus and infraspinatus tendons. Rats were then gradually returned to their overuse protocol. Quantitative ambulatory measures including medial/lateral, propulsion, braking, and vertical forces were significantly different between groups. Additionally, cartilage and adjacent tendon properties were significantly altered. These results identify joint imbalance as a mechanical mechanism for joint damage and demonstrate the importance of preserving rotator cuff balance when treating active cuff tear patients. (c) 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:638-644, 2014.
Metrics
Details
- Title
- Disruption of the Anterior-Posterior Rotator Cuff Force Balance Alters Joint Function and Leads to Joint Damage in a Rat Model
- Creators
- Katherine E. Reuther - University of PennsylvaniaStephen J. Thomas - University of PennsylvaniaJennica J. Tucker - University of PennsylvaniaJoseph J. Sarver - University of PennsylvaniaChancellor F. Gray - University of PennsylvaniaSarah I. Rooney - University of PennsylvaniaDavid L. Glaser - University of PennsylvaniaLouis J. Soslowsky - University of Pennsylvania
- Publication Details
- Journal of orthopaedic research, v 32(5), pp 638-644
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- P30AR050950 / Penn Center for Musculoskeletal Disorders R01AR056658 / NIH/NIAMS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS) P30AR050950 / NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000332842300004
- Scopus ID
- 2-s2.0-84899421109
- Other Identifier
- 991019176644504721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Orthopedics