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Journal article
Dissociable brain states linked to common and creative object use
Human brain mapping, v 32(4), pp 665-675
Apr 2011
PMID: 20533561
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Studies of conceptual processing have revealed that the prefrontal cortex is implicated in close-ended, deliberate memory retrieval, especially the left ventrolateral prefrontal regions. However, much of human thought-particularly that which is characterized as creative-requires more open-ended, spontaneous memory retrieval. To explore the neural systems that support conceptual processing under these two distinct circumstances, we obtained functional magnetic resonance images from 24 participants either while retrieving the common use of an everyday object (e.g., "blowing your nose," in response to a picture of a tissue) or while generating a creative (i.e., uncommon but plausible) use for it (e.g., "protective padding in a package"). The patterns of activation during open- and closed-ended tasks were reliably different, with regard to the magnitude of anterior versus posterior activation. Specifically, the close-ended task (i.e., Common Use task) reliably activated regions of lateral prefrontal cortex, whereas the open-ended task (i.e., Uncommon Use task) reliably activated regions of occipito-temporal cortex. Furthermore, there was variability across subjects in the types of responses produced on the open-ended task that was associated with the magnitude of activation in the middle occipital gyrus on this task. The present experiment is the first to demonstrate a dynamic tradeoff between anterior frontal and posterior occipitotemporal regions brought about by the close- or open-ended task demands.
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Details
- Title
- Dissociable brain states linked to common and creative object use
- Creators
- Evangelia G Chrysikou - University of PennsylvaniaSharon L Thompson-Schill
- Publication Details
- Human brain mapping, v 32(4), pp 665-675
- Publisher
- Wiley
- Grant note
- R21 MH083029 / NIMH NIH HHS R01 DC009209 / NIDCD NIH HHS R01-DC009209 / NIDCD NIH HHS MH083029 / NIMH NIH HHS R01-DC009209R21 / NIDCD NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Arts and Sciences
- Web of Science ID
- WOS:000288177300014
- Scopus ID
- 2-s2.0-79952404378
- Other Identifier
- 991020531994504721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Neuroimaging
- Neurosciences
- Radiology, Nuclear Medicine & Medical Imaging