Journal article
Do Neighborhood Socioeconomic Deprivation and Low Social Cohesion Predict Coronary Calcification?
American journal of epidemiology, v 172(3), pp 288-298
01 Aug 2010
PMID: 20610467
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Growing evidence suggests that neighborhood characteristics may influence the risk of coronary heart disease. No studies have yet explored associations of neighborhood attributes with subclinical atherosclerosis in younger adult populations. Using data on 2,974 adults (1,699 women, 1,275 men) aged 32-50 years in 2000 from the Coronary Artery Disease Risk Development in Young Adults (CARDIA) Study and 2000 US Census block-group-level data, the authors estimated multivariable-adjusted associations of neighborhood socioeconomic deprivation and perceived neighborhood cohesion with odds of coronary artery calcification (CAC) 5 years later. Among women, the quartiles of highest neighborhood deprivation and lowest cohesion were associated with higher odds of CAC after adjustment for individual-level demographic and socioeconomic factors (for deprivation, odds ratio = 2.49, 95% confidence interval: 1.22, 5.08 (P for trend = 0.03); for cohesion, odds ratio = 1.87, 95% confidence interval: 1.10, 3.16 (P for trend = 0.02)). Associations changed only slightly after adjustment for behavioral, psychosocial, and biologic factors. Among men, neither neighborhood deprivation nor cohesion was related to CAC. However, among men in deprived neighborhoods, low cohesion predicted higher CAC odds (for interaction between neighborhood deprivation and cohesion, P = 0.03). This study provides evidence on associations of neighborhood deprivation and cohesion with CAC in younger, asymptomatic adults. Neighborhood attributes may contribute to subclinical atherosclerosis.
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Details
- Title
- Do Neighborhood Socioeconomic Deprivation and Low Social Cohesion Predict Coronary Calcification?
- Creators
- Daniel Kim (Corresponding Author) - Harvard UniversityAna V. Diez Roux - University of MichiganCatarina I. Kiefe - University of Massachusetts Chan Medical SchoolIchiro Kawachi - Harvard UniversityKiang Liu - Northwestern University
- Publication Details
- American journal of epidemiology, v 172(3), pp 288-298
- Publisher
- Oxford University Press
- Number of pages
- 11
- Grant note
- John D. and Catherine T. MacArthur Foundation Research Network on Socioeconomic Status and Health R01HL048049 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) N01HC045134 / DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) N01-HC-05187; N01-HC-45134; N01-HC-48047; N01-HC-48048; N01-HC-48049; N01-HC-48050; N01-HC-95095; K99HL089459 / National Heart, Lung, and Blood Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Epidemiology and Biostatistics
- Web of Science ID
- WOS:000280531100007
- Scopus ID
- 2-s2.0-77955142517
- Other Identifier
- 991020112259704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health