Journal article
Does serum prolactin indicate the presence of seizure in the emergency department patient?
Journal of neurology, v 251(6), pp 736-739
01 Jun 2004
PMID: 15311351
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We sought to evaluate whether there was a correlation between elevated serum prolactin in patients presenting with the question of seizure.
A Convenience sample of 200 consecutive patients were chosen who had a serum prolactin measurement in the setting of seizure activity.
The prolactin level was within a range of 3.90-294.00 mg/dl with an upper limit of normal being 29.9 mg/dl. Patients were ultimately diagnosed with seizure in 54.5% (109 of 200) with an abnormal prolactine in 31.0% (62 of 200). The sensitivity of this serum prolactin was 42%, the specificity was 82%, positive predictive value (PPV) of 74%, and negative predictive value (NPV) of 54%. There was an overall accuracy of 60% in the diagnosis of seizure, with a likelihood ratio of 2.4 (95% Confidence Interval [CI], 1.5-3.9).
The measurement of serum prolactin is helpful as a confirmatory test, but not as screening test in the emergency department setting.
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Details
- Title
- Does serum prolactin indicate the presence of seizure in the emergency department patient?
- Creators
- Rade B Vukmir - University of Pittsburgh Medical Center
- Publication Details
- Journal of neurology, v 251(6), pp 736-739
- Publisher
- Springer Nature
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Emergency Medicine
- Web of Science ID
- WOS:000222251000014
- Scopus ID
- 2-s2.0-3042621460
- Other Identifier
- 991021903267704721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Clinical Neurology