Logo image
Does the histamine skin prick test identify patients at risk for toxicity after the ingestion of astemizole?
Journal article   Peer reviewed

Does the histamine skin prick test identify patients at risk for toxicity after the ingestion of astemizole?

JOSEPH Melvin, RAN Anbar and JACK Becker
Pediatric emergency care, v 10(3), pp 166-167
Jun 1994
PMID: 8058561

Abstract

Astemizole is a widely prescribed nonsedating antihistamine that suppresses wheal and flare reactions from histamine prick testing. We report a two-year-old girl with a serum concentration-proven overdose of astemizole who nonetheless exhibited a significant wheal and flare reaction after histamine skin prick testing for at least 22 hours after the ingestion. These findings suggest that histamine skin prick testing should not be used as a screening test to evaluate whether an ingestion of astemizole has occurred.

Metrics

4 Record Views

Details

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Web of Science research areas
Emergency Medicine
Pediatrics
Logo image