Journal article
Dofetilide and Flecainide Combination: The Serendipity of Successful Treatment of Atrial Fibrillation After Failed Ablation
Canadian journal of cardiology, v 41(2), pp 212-214
01 Feb 2025
PMID: 39549951
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Antiarrhythmic drugs (AADs) and catheter ablation (CA) are guideline-directed rhythm control treatments for atrial fibrillation (AF). AADs are rarely used in combination to treat AF. Dofetilide (class III agent) and flecainide (class Ic agent) are contraindicated in patients with renal dysfunction and coronary artery disease, respectively. We describe a case of a patient who refused nonpharmacological treatment for recurrent AF after CA, but was treated successfully with a dofetilide and flecainide combination. The patient's taking the combination was serendipitous initially. Both drugs were continued nonetheless, because it was the combination and not the individual drug that controlled AF in our patient.
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Details
- Title
- Dofetilide and Flecainide Combination: The Serendipity of Successful Treatment of Atrial Fibrillation After Failed Ablation
- Creators
- Daniel A. N. Mascarenhas - Drexel UniversityBharat K. Kantharia (Corresponding Author) - Icahn School of Medicine at Mount Sinai
- Publication Details
- Canadian journal of cardiology, v 41(2), pp 212-214
- Publisher
- Elsevier
- Number of pages
- 3
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Cardiology
- Web of Science ID
- WOS:001426312700001
- Scopus ID
- 2-s2.0-85211220833
- Other Identifier
- 991022197305904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems