Journal article
Dopamine stimulates phosphoinositide metabolism in rat brain
Neuroscience research communications, Vol.6(2), pp.69-75
01 Jan 1990
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Striatal slices prepared from male Sprague-Dawley rats were prelabeled with 2-( super(3)H)-inositol treated with various dopaminergic agents, and the content of inositol phosphates determined by Dowex anion exchange chromatography. Dopamine, apomorphine, and SKF38393 each significantly increased the level of accumulated inositol phosphates, whereas the D sub(2) receptor-selective agonist, quinpirole, had no effect. The results suggest that dopaminergic agonists, acting probably through a D sub(1) receptor in the rat striatum, stimulate the metabolism of phosphoinositides with the generation of secondary messengers.
Metrics
1 Record Views
Details
- Title
- Dopamine stimulates phosphoinositide metabolism in rat brain
- Creators
- A UndieE Friedman
- Publication Details
- Neuroscience research communications, Vol.6(2), pp.69-75
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pharmacology and Physiology
- Identifiers
- 991019184027704721
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Web of Science research areas
- Neurosciences