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Double-blind study of clozapine dose response in chronic schizophrenia
Journal article   Peer reviewed

Double-blind study of clozapine dose response in chronic schizophrenia

George Simpson, Richard Josiassen, Joseph Stanilla and Jose de Leon
The American journal of psychiatry, v 156(11), pp 1744-1750
01 Nov 1999
PMID: 10553738

Abstract

Drug therapy Psychiatry Schizophrenia
Fifty patients who met Kane et al.'s criteria for treatment-refractory schizophrenia or schizoaffective disorder were studied. All subjects were randomly assigned to 100, 300, or 600 mg/day of clozapine for 16 weeks of double-blind treatment. Forty-eight patients completed this first 16 weeks. Of the 50 patients, 36 went on to second and third 16-week trials of double-blind treatment at the remaining doses.

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Collaboration types
Domestic collaboration
Web of Science research areas
Psychiatry
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