Journal article
Drug-associated renal dysfunction and injury
Nature clinical practice. Nephrology, v 2(2), pp 80-91
Feb 2006
PMID: 16932399
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Renal dysfunction and injury secondary to medications are common, and can present as subtle injury and/or overt renal failure. Some drugs perturb renal perfusion and induce loss of filtration capacity. Others directly injure vascular, tubular, glomerular and interstitial cells, such that specific loss of renal function leads to clinical findings, including microangiopathy, Fanconi syndrome, acute tubular necrosis, acute interstitial nephritis, nephrotic syndrome, obstruction, nephrogenic diabetes insipidus, electrolyte abnormalities and chronic renal failure. Understanding the mechanisms involved, and recognizing the clinical presentations of renal dysfunction arising from use of commonly prescribed medications, are important if injury is to be detected early and prevented. This article reviews the clinical features and basic processes underlying renal injury related to the use of common drugs.
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Details
- Title
- Drug-associated renal dysfunction and injury
- Creators
- Devasmita Choudhury - The University of Texas Southwestern Medical CenterZiauddin Ahmed - Drexel University
- Publication Details
- Nature clinical practice. Nephrology, v 2(2), pp 80-91
- Publisher
- Springer Nature
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Nephrology (and Hypertension)
- Web of Science ID
- WOS:000235515600011
- Scopus ID
- 2-s2.0-33644829720
- Other Identifier
- 991019173974904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Urology & Nephrology