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Duct detection and wall spacing estimation in breast tissue
Journal article   Peer reviewed

Duct detection and wall spacing estimation in breast tissue

L Huang, K D Donohue, V Genis and F Forsberg
Ultrasonic imaging, v 22(3), pp 137-152
Jul 2000
PMID: 11297148

Abstract

Algorithms Breast Neoplasms - diagnostic imaging Breast Neoplasms - pathology Carcinoma, Ductal, Breast - diagnostic imaging Carcinoma, Ductal, Breast - pathology Diagnosis, Differential Female Humans Monte Carlo Method Phantoms, Imaging ROC Curve Signal Processing, Computer-Assisted Ultrasonography, Mammary - methods
The relationship between duct tissue and several types of malignant disease suggests that methods for characterizing duct structures may be useful tools in ultrasonic tissue characterization. This paper presents performance results from ultrasonic phantom experiments and Monte Carlo simulations for detecting and estimating duct wall spacings on the order of those typically found in breast tissue using methods based on the generalized spectrum (GS) and cepstrum. A performance comparison demonstrates the advantages of each method and examines the effects of various signal processing options, including a special normalization technique for the GS that effectively whitens the data spectrum and reduces interfering spectral influences with little overall performance loss. Experimental results (for both simulation and phantom) indicate that the GS typically achieves detection rates of over 90% (at 10% false alarm rates) over a broad range of SNR values (3-21 dB). The GS detection performance exceeds that of the cepstrum and exhibits more robustness to noise and signal processing parameters. Simulation results with fixed system effects indicate better estimation performance for cepstral-based methods, while experimental phantom results show the GS estimation performance to be the same or better than the cepstral-based method.

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Collaboration types
Domestic collaboration
Web of Science research areas
Acoustics
Engineering, Biomedical
Radiology, Nuclear Medicine & Medical Imaging
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