Journal article
Dynamic Evaluation of a Digital Wireless Intracranial Pressure Sensor for the Assessment of Traumatic Brain Injury in a Swine Model
IEEE transactions on microwave theory and techniques, v 61(1), pp 316-325
01 Jan 2013
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The monitoring and control of increased intracranial pressure (ICP) are the major requirements for the diagnosis and treatment of patients suffering from traumatic brain injury (TBI) or hydrocephalus. Widely used commercially available ICP measuring devices require the use of a tethered fiber optic probe, which can cause complications, such as infection and hemorrhage. The use of a probe also prohibits immediate (at the time of induced injury) and long-term measurements of ICP. Therefore, we have developed and tested a small fully embedded wireless ICP sensor, incorporating a novel antenna and packaging arrangement. Evaluations were performed in-vitro and in-vivo to demonstrate the robustness of this microwave pressure-monitoring system. This is the first report of in-vivo tests in a dynamic study of continuous (every 6 s) wireless ICP measurements in a swine model of closed-head rotational-acceleration induced TBI using a digital device. In particular, our device measured extreme changes in ICP immediately upon rapid head rotation that persisted for hours after the injury. The readings matched well those obtained from a commercially available tethered monitor. Our device can be utilized in the future as a tool to diagnose and track long-term ICP changes.
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Details
- Title
- Dynamic Evaluation of a Digital Wireless Intracranial Pressure Sensor for the Assessment of Traumatic Brain Injury in a Swine Model
- Creators
- Xu Meng - Drexel Univ, Sch Biomed Engn, Philadelphia, PA 19104 USAKevin D. Browne - University of PennsylvaniaShi-Min Huang - Drexel UniversityConstance Mietus - University of PennsylvaniaD. Kacy Cullen - University of PennsylvaniaMohammad-Reza Tofighi - Pennsylvania State UniversityArye Rosen - Drexel University
- Publication Details
- IEEE transactions on microwave theory and techniques, v 61(1), pp 316-325
- Publisher
- IEEE
- Number of pages
- 10
- Grant note
- Department of Neurosurgery, University of Pennsylvania NS050598 / National Institutes of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA University Research Foundation, University of Pennsylvania
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Electrical and Computer Engineering
- Web of Science ID
- WOS:000313940300034
- Scopus ID
- 2-s2.0-84872841502
- Other Identifier
- 991022065640504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Engineering, Electrical & Electronic