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Dynamic of alpha -tubulin deacetylation in intact neurons
Journal article   Peer reviewed

Dynamic of alpha -tubulin deacetylation in intact neurons

M Black, P Baas and S Humphries
The Journal of neuroscience, Vol.9(1), pp.358-368
01 Jan 1989

Abstract

The majority of the alpha -tubulin in cultured neurons is acetylated. The present studies examine the relationships of the acetylation and deacetylation reactions to tubulin assembly and disassembly in intact neurons. The authors suggest that these kinetically distinguishable pools of acetylated alpha -tubulin reflect distinct pools of acetylated microtubules that differ in their average rates of subunit turnover.

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