Journal article
Dysphonia due to kaposi's sarcoma as the presenting symptom of human immunodeficiency virus
Journal of voice, v 18(3), pp 398-402
2004
PMID: 15331114
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Dysphonia and airway obstruction are rarely caused by Kaposi's Sarcoma (KS). We present the case of a 40 year old man receiving his diagnosis of human immunodeficiency virus (HIV) after presenting with hoarseness caused by laryngeal KS. HIV may contribute to KS growth by stimulating excess production of angiogenic lymphokines and monokines and by decreasing immune surveillance. Histopathology reveals proliferating endothelial cells, fibroblasts, thin vascular slits, and extravasated erythrocytes. A wide variety of localized treatment options exist, while chemotherapeutic agents and
alpha-interferon are used for multifocal or widespread disease.
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Details
- Title
- Dysphonia due to kaposi's sarcoma as the presenting symptom of human immunodeficiency virus
- Creators
- Joseph R. Watson - Philadelphia College of Osteopathic MedicineDavid Granoff - Philadelphia College of Osteopathic MedicineRobert Thayer Sataloff - Department of Otolaryngology-Head and Neck Surgery (ORL-HNS), Thomas Jefferson University and Department of ORL-HNS, Graduate Hospital, Philadelphia, PA
- Publication Details
- Journal of voice, v 18(3), pp 398-402
- Publisher
- Mosby, Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000223988900016
- Scopus ID
- 2-s2.0-4444296515
- Other Identifier
- 991019312334004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Audiology & Speech-language Pathology
- Otorhinolaryngology