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EMERGING FINDINGS FROM THE COPE-CT STUDY: COHORT CHARACTERISTICS & INTERVENTION EFFECTS ON OUTCOMES
Journal article   Open access   Peer reviewed

EMERGING FINDINGS FROM THE COPE-CT STUDY: COHORT CHARACTERISTICS & INTERVENTION EFFECTS ON OUTCOMES

R H Fortinsky, L N Gitlin, J A Grady, C V Piersol, L T Pizzi and J T Robison
Innovation in aging, v 2(Suppl 1), pp 822-822
11 Nov 2018
DOI: https://doi.org/10.1093/geroni/igy023.3059
url
https://academic.oup.com/innovateage/article-pdf/2/suppl_1/822/26476037/igy023.3059.pdfView
Published, Version of Record (VoR) Open
url
https://doi.org/10.1093/geroni/igy023.3059View
Published, Version of Record (VoR) Open

Abstract

Abstracts
This presentation provides an overview of the COPE-CT translational study design elements that reflect pragmatic trial approaches, and reports study cohort baseline characteristics and COPE effects on immediate (4-month post-randomization) outcomes. Study enrollment ended in February 2018—291 dyads were randomized, achieving recruitment goals—and immediate outcome data will be available in July 2018. Primary study outcome is level of functional independence for persons with dementia, measured using the Caregiver Assessment of Function and Upset (CAFU) score, as was used in the original COPE efficacy trial; scores range from 1–7, higher scores=greater independence. Selected baseline characteristics: 77% of persons with dementia (N=291) and 69% of caregivers (N=291) female; mean(s.d.) ages=85.0(8.0) for persons with dementia and 62.2(11.3) for caregivers; 16% of persons with dementia and 17% of caregivers self-reported as Black; 54% of caregivers daughters, 18% sons, 18% spouses. Mean(s.d.) baseline CAFU score=2.91(1.17). Implications of emerging outcome-based findings will be discussed.

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