Journal article
EXERT-BC: Prospective Study of an Exercise Regimen After Treatment for Breast Cancer
Sports medicine international open, v 8(CP), a21930922
2024
PMID: 38312924
Abstract
Abstract
Purpose EXERT-BC is a dose-escalated resistance training regimen created to
improve body composition, strength, and balance in women treated for breast
cancer (BC). Herein, we report the interim analysis. Women treated for BC
underwent this 3-month exercise regimen in an exercise oncology facility with
continual monitoring of load and strength. Twenty women completed the
IRB-approved protocol, with a mean age of 57 years (range 41–74).
Concurrent therapies included anti-estrogen therapy (73%), chemotherapy
(14%), and radiotherapy (23%). 27% of women endorsed
prior exercise. Subjects missed an average of 1.75 classes (range 0–7),
with all meeting adherence over 75%. No injuries or adverse events were
reported aside from muscle soreness and 2 days of knee pain. Significant
differences in body composition at completion included reduced body fat
(38.2% vs. 36.7%, p=0.003), and increased muscle mass
(33.1% vs. 37.1%, p<0.001), functional mobility
screening (9.82 vs. 11.73, p=0.018), and Y-balance (left: 72.4 vs. 85.3,
p=0.001; right: 70.3 vs. 85.2. p<0.001). Significant increases
in load were demonstrated: split squat (p<0.001), trap bar deadlift
(p=0.035), inclined dumbbell press (p<0.001), and bird dog rows
(p<0.001). Dose-escalated resistance training in women with BC is safe
and feasible, endorsing significant improvements across body composition,
balance, and strength.
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Details
- Title
- EXERT-BC: Prospective Study of an Exercise Regimen After Treatment for Breast Cancer
- Creators
- Colin E. Champ - Allegheny Health NetworkChris Peluso - Allegheny Health NetworkDavid J. Carenter - Duke Medical CenterJared Rosenberg - Syracuse UniversityFrank Velasquez - Allegheny Health NetworkAdam Annichine - Allegheny Health NetworkKrista Matsko - Allegheny Health NetworkParker N. Hyde - University of North GeorgiaAlexander K. Diaz - Duke Medical CenterSushil Beriwal - Allegheny Health NetworkChristie Hilton - Allegheny Health Network
- Publication Details
- Sports medicine international open, v 8(CP), a21930922
- Publisher
- Thieme
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Other Identifier
- 991021897390304721