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Journal article
Early diagnosis of traumatic intracranial hematomas
Journal of biomedical optics, v 24(5), pp 1-10
01 May 2019
PMID: 30719879
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Timing of the intervention for intracranial hematomas is critical for its success, specifically since expansion of the hemorrhage can result in debilitating and sometimes fatal outcomes. Led by Britton Chance, we and an extended team from University of Pennsylvania, Baylor and Drexel universities developed a handheld brain hematoma detector for early triage and diagnosis of head trauma victims. After obtaining de novo Food and Drug Administration clearance, over 200 systems are deployed in all Marine battalion aid stations around the world. Infrascanner, a handheld brain hematoma detection system, is based on the differential near-infrared light absorption of the injured versus the noninjured part of brain. About 12 independent studies have been conducted in the USA, Canada, Spain, Italy, the Netherlands, Germany, Russia, Poland, Afghanistan, India, China, and Turkey. Here, we outline the background and design of the device as well as clinical studies with a total of 1293 patients and 203 hematomas. Infrascanner demonstrates high sensitivity (adults: 92.5% and children: 93%) and specificity (adults: 82.9% and children: 86.5%) in detecting intracranial hematomas >3.5 mL in volume and <2.5 cm from the surface of the brain. Infrascanner is a clinically effective screening solution for head trauma patients in prehospital settings where timely triage is critical. (C) The Authors. Published by SPIE undera Creative Commons Attribution 4.0 Unported License.
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Details
- Title
- Early diagnosis of traumatic intracranial hematomas
- Creators
- Hasan Ayaz - Children's Hospital of PhiladelphiaMeltem Izzetoglu - Drexel UniversityKurtulus Izzetoglu - Drexel UniversityBanu Onaral - Drexel UniversityBaruch Ben Dor - Infrascan
- Publication Details
- Journal of biomedical optics, v 24(5), pp 1-10
- Publisher
- Spie-Soc Photo-Optical Instrumentation Engineers
- Number of pages
- 10
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000481880600011
- Scopus ID
- 2-s2.0-85061044292
- Other Identifier
- 991019168466304721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biochemical Research Methods
- Optics
- Radiology, Nuclear Medicine & Medical Imaging