Life Sciences & Biomedicine Public, Environmental & Occupational Health Science & Technology
Recent research has implicated economic insecurity in increasing midlife death rates and "deaths of despair," including suicide, chronic liver disease, and drug and alcohol poisoning. In this ecological longitudinal study, we evaluated the association between changes in economic insecurity and increases in deaths of despair and midlife all-cause mortality in US counties during 2000-2015. We extended a previously developed measure of economic insecurity using indicators from the Census and Federal Reserve Bank in US counties for the years 2000 and 2010. Linear regression models were used to estimate the association of change in economic insecurity with change in death rates through 2015. Counties experiencing elevated economic insecurity in either 2000 or 2010 had higher rates of deaths of despair and all-cause midlife mortality at baseline but similar rates of increase in deaths of despair from 2001 to 2015 compared with counties with stable low economic insecurity. Counties in the highest tertile of economic insecurity in 2000 and 2010 had 41% (95% confidence interval: 1.36, 1.47) higher midlife mortality rates at baseline and a rate of increase of 2% more per 5-year period (95% confidence interval: 1.00, 1.03) than counties with stable low economic insecurity. Economic insecurity may represent a population-level driver of US death trends.
Economic Insecurity and Deaths of Despair in US Counties
Creators
Emily A. Knapp - Johns Hopkins University
Usama Bilal - Drexel University
Lorraine T. Dean - Johns Hopkins University
Mariana Lazo - Johns Hopkins Medicine
David D. Celentano - Johns Hopkins University
Publication Details
American journal of epidemiology, v 188(12), pp 2131-2139
Publisher
Oxford Univ Press
Number of pages
9
Grant note
T32DK062707 / Clinical Research and Epidemiology in Diabetes and Endocrinology training grant
DP5OD26429 / Office of the Director of the National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
Deloitte from the Ministry of Public Health, State of Qatar
P30AI094189 / Johns Hopkins University Center for AIDS Research
DP5OD026429 / OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
R01DA012568 / NATIONAL INSTITUTE ON DRUG ABUSE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA); European Commission
Johns Hopkins Center for a Livable Future-Lerner Fellowship
K01CA184288 / National Cancer Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
P30CA006973 / Sidney Kimmel Cancer Center
R25MH083620 / National Institute of Mental Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
P30AI094189; 5U10AA025286; 1U01DA036297; R01DA012568; R01DA0430898; 1U24OD023382; R012DA041034; 1U01DA040325 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
T32DK062707 / NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
P30CA006973 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
P30AI094189 / NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID)
Resource Type
Journal article
Language
English
Academic Unit
Urban Health Collaborative
Web of Science ID
WOS:000518547500010
Scopus ID
2-s2.0-85078492274
Other Identifier
991019167668404721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool: