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Journal article
Effect of Inapparent Murine Hepatitis Virus Infections on Macrophages and Host Resistance
Journal of leukocyte biology, v 39(5), pp 559-565
01 May 1986
PMID: 3009672
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Inapparent infections of mice with murine hepatitis virus (MHV) altered host resistance to experimental infection with a second virus, encephalomyocarditis virus (EMC), reduced the protective effects of exogeneously administered interferon against EMC infections, and it altered macrophage ectoenzyme phenotypes in two macrophage populations. Resident peritoneal macrophages from mice experimentally infected with one of two strains of MHV also demonstrated altered ectoenzyme phenotypes. These data demonstrate that inapparent infections with MHV alter several host resistance and macrophage parameters and directly demonstrate that effects of inapparent MHV infection on macrophage parameters can be reproduced experimentally.
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Details
- Title
- Effect of Inapparent Murine Hepatitis Virus Infections on Macrophages and Host Resistance
- Creators
- Walla L. Dempsey - Drexel UniversityAbigail L. Smith - Yale UniversityPage S. Morahan - Drexel University
- Publication Details
- Journal of leukocyte biology, v 39(5), pp 559-565
- Publisher
- John Wiley and Sons Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1986A926500008
- Scopus ID
- 2-s2.0-0022572493
- Other Identifier
- 991019184191904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Cell Biology
- Hematology
- Immunology