Journal article
Effect of Physical Activity on the Relation Between Psychosocial Factors and Cardiovascular Events (from the Multi-Ethnic Study of Atherosclerosis)
The American journal of cardiology, v 117(10), pp 1545-1551
15 May 2016
PMID: 27017324
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Depression, chronic stress, and low levels of social support have known associations with cardiovascular disease (CVD). Physical activity has been shown to promote psychological health, reduce the frequency of depressive symptoms, and is associated with fewer cardiovascular events in depressed subjects with known CVD. The purpose of the present study was to test the hypothesis that physical activity attenuates the association between psychosocial factors and incident CVD. The Multi-Ethnic Study of Atherosclerosis cohort includes 6,814 participants free of clinical CVD at baseline. Complete data on physical activity were available for 6,795 subjects (mean age 62 years; 47% men). Psychosocial factors were assessed using standardized questionnaires. Cox proportional hazard models were used to evaluate the association between psychosocial factors and CVD events and its modulation by physical activity. In models adjusted for age, gender, and race/ethnicity, both depression and chronic burden were associated with CVD events (hazard ratio [HR] = 1.38 [1.04 to 1.84], p = 0.028 for depression; HR = 1.15 [1.05 to 1.24], p = 0.001 for chronic burden). Adjusting for physical activity, the relation between depression, chronic burden, and CVD events was not significantly reduced (HR = 1.35 [1.02 to 1.80], p = 0.039 for depression; HR = 1.14 [1.05 to 1.23], p = 0.001 for chronic burden). Although physical activity is an important component of physical and psychological health and well-being, it did not significantly attenuate the strong relation between depression or chronic burden and incident CVD.
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Details
- Title
- Effect of Physical Activity on the Relation Between Psychosocial Factors and Cardiovascular Events (from the Multi-Ethnic Study of Atherosclerosis)
- Creators
- Randy Cohen - St. Luke's-Roosevelt Hospital CenterNatalie C Gasca - University of WashingtonRobyn L McClelland - University of WashingtonCarmela Alcántara - Columbia UniversityDavid R Jacobs, Jr - Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MinnesotaAna Diez Roux - Drexel UniversityAlan Rozanski - St. Luke's-Roosevelt Hospital CenterSteven Shea - Columbia University
- Publication Details
- The American journal of cardiology, v 117(10), pp 1545-1551
- Publisher
- Elsevier
- Grant note
- N01HC95169 / NHLBI NIH HHS N01HC95161 / NHLBI NIH HHS N01HC95164 / NHLBI NIH HHS N01HC95160 / NHLBI NIH HHS N01HC95167 / NHLBI NIH HHS N01HC95159 / NHLBI NIH HHS N01 HC095159 / NHLBI NIH HHS N01HC95163 / NHLBI NIH HHS N01HC95166 / NHLBI NIH HHS P60 MD002249 / NIMHD NIH HHS N01HC95168 / NHLBI NIH HHS UL1 TR000040 / NCATS NIH HHS UL1 TR001079 / NCATS NIH HHS N01HC95165 / NHLBI NIH HHS N01HC95162 / NHLBI NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000376219300001
- Scopus ID
- 2-s2.0-84962564543
- Other Identifier
- 991019169163504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems