Journal article
Effect of Rosuvastatin on C-Reactive Protein and Renal Function in Patients With Chronic Kidney Disease
The American journal of cardiology, v 96(9), pp 1290-1292
2005
PMID: 16253600
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The purpose of this 20-week, open-label, randomized clinical trial was to evaluate the effect of rosuvastatin on fasting serum lipids and lipoproteins, high-sensitivity C-reactive protein (hs-CRP), and the glomerular filtration rate (GFR) in 91 patients with chronic kidney disease. Patients were randomized to rosuvastatin 10 mg/day (n = 48) or to no lipid-lowering treatment (n = 43) for 20 weeks. In contrast to patients not receiving rosuvastatin, patients receiving rosuvastatin tended to derive more favorable improvements from baseline values in low-density lipoprotein cholesterol (−43%, p <0.001, vs 7%, p = NS; p <0.001 for change with rosuvastatin treatment vs change with no antilipemic treatment), hs-CRP (−47%, p <0.001, vs 7%, p = NS; p <0.001 for change with rosuvastatin treatment vs change with no antilipemic treatment), and GFR (11%, p <0.05, vs 4%, p = NS; p = NS for change with rosuvastatin treatment vs change with no antilipemic treatment).
Metrics
Details
- Title
- Effect of Rosuvastatin on C-Reactive Protein and Renal Function in Patients With Chronic Kidney Disease
- Creators
- Anil Verma - Candler Internal Medicine, Metter, GeorgiaKarthik M. Ranganna - Candler Internal Medicine, Metter, GeorgiaRani S. Reddy - Candler Internal Medicine, Metter, GeorgiaMandeep Verma - Candler Internal Medicine, Metter, GeorgiaNeil F. Gordon - St. Joseph’s Candler Hospital
- Publication Details
- The American journal of cardiology, v 96(9), pp 1290-1292
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:000233343500023
- Scopus ID
- 2-s2.0-27144534466
- Other Identifier
- 991019299102304721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems