Files and links (2)
Published, Version of Record (VoR)Open Access (License Unspecified), Open
Journal article
Effect of age on cytokine production in humans
Age, v 21(4), pp 137-151
01 Oct 1998
PMID: 23604376
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Aging is accompanied by many changes in immune response, with the most consistent and dramatic alterations occurring within the T cell compartment. Since cytokines are central to immune cell communications, age-associated changes in cytokine production may contribute to these alterations. While data from murine studies suggest a switch from a Th1 (IL-2, IFNγ) to a Th2 (IL-4, IL-6, IL-10) cytokine response, this model has not been as clearly established in humans. In addition, this current review of over 50 studies in humans suggests that age-associated changes in cytokine production are not consistent.
Metrics
Details
- Title
- Effect of age on cytokine production in humans
- Creators
- Erica D. Bernstein - Hahnemann University HospitalDonna M. Murasko - Hahnemann University Hospital
- Publication Details
- Age, v 21(4), pp 137-151
- Publisher
- Kluwer Academic Publishers
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biology
- Web of Science ID
- WOS:000079338700001
- Scopus ID
- 2-s2.0-0032462502
- Other Identifier
- 991020950771104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Geriatrics & Gerontology