Journal article
Effect of photobiomodulation therapy on inflammatory cytokines in healing dynamics of diabetic wounds: a systematic review of preclinical studies
Archives of physiology and biochemistry, Vol.129(3), pp.663-670
04 May 2023
PMID: 33370535
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Delayed wound healing in diabetes mellitus (DM) is due to the overlapping phases of the healing process. The prolonged inflammation and altered levels of inflammatory cytokines lead to deformed cell proliferation. Photobiomodulation alleviates the expression of inflammatory cytokines and promotes tissue repair, thereby restoring the wound healing process.
To find out the effect of photobiomodulation therapy (PBMT) in the healing dynamics of diabetic wounds with particular emphasis on interleukin-6, interleukin-1β, and tumour necrosis factor-α.
Scientific databases searched using keywords of the population: DM, intervention: PBMT, and outcomes: inflammatory cytokines.
We have included five preclinical studies in the present systematic review for qualitative analysis. These studies evaluated the effect of PBMT at different wavelengths, dosage, and time on wound healing in DM.
The systematic review concludes that PBMT regulates inflammatory cytokines levels, enhances cell proliferation, and migration, thereby improving the wound healing properties.
Metrics
1 Record Views
Details
- Title
- Effect of photobiomodulation therapy on inflammatory cytokines in healing dynamics of diabetic wounds: a systematic review of preclinical studies
- Creators
- Gagana Karkada - Manipal UniversityG. Arun Maiya - Department of Physiotherapy, Centre for Diabetic Foot Care and Research, Manipal College of Health Professions, Manipal Academy of Higher EducationNicolette N. Houreld - University of JohannesburgPraveen Arany - University at Buffalo, State University of New YorkMohandas Rao KG - Department of Anatomy, Melaka Manipal Medical College-Manipal Campus, Manipal Academy of Higher EducationShalini Adiga - Manipal Academy of Higher EducationShobha Ullas Kamath - Manipal Academy of Higher EducationSomashekar Shetty - Manipal Academy of Higher Education
- Publication Details
- Archives of physiology and biochemistry, Vol.129(3), pp.663-670
- Publisher
- Taylor & Francis
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000603803000001
- Scopus ID
- 2-s2.0-85098600255
- Other Identifier
- 991022059934004721
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Biochemistry & Molecular Biology
- Biophysics
- Endocrinology & Metabolism
- Physiology