Journal article
Effect of surgical revascularization in patients with coronary artery disease and ventricular tachycardia or fibrillation in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry
The American heart journal, v 143(5), pp 821-826
01 May 2002
PMID: 12040343
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
BackgroundPatients who undergo resuscitation from near-fatal ventricular arrhythmias often have significant coronary artery disease, and revascularization has been shown to reduce myocardial ischemia and cardiac arrest episodes in this patient population. The magnitude of benefit attributed to revascularization has varied by study, and the use of adjunct implantable cardioverter defibrillator (ICD) therapy has not been well-characterized.Methods and ResultsThe Antiarrhythmics Versus Implantable Defibrillators (AVID) registry included 3117 patients with life-threatening ventricular arrhythmias, of whom 2321 (77%) had documented coronary artery disease and 281 (17%) underwent a coronary artery bypass grafting revascularization procedure after the index event. Patients who underwent a revascularization procedure were younger, had a lower incidence rate of prior myocardial infarction and ventricular arrhythmia, had a higher left ventricular ejection fraction, had less congestive heart failure, and were more likely to have had ventricular fibrillation as the presenting arrhythmia. Patients who underwent revascularization had a better survival rate than did those who did not undergo such a procedure after the index event, and adjustment for differing baseline patient covariates did not alter the relative survival rate benefit. Further, ICD implantation offered a similar survival rate advantage to those patients in the AVID registry with coronary artery disease independent of revascularization.ConclusionCoronary revascularization in the AVID registry patients with coronary artery disease effected a survival rate benefit that was not attributable to differences in baseline patient characteristics. The benefit of ICD on patient survival rate was not attenuated by a revascularization procedure. (Am Heart J 2002;143:821-6.)
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Details
- Title
- Effect of surgical revascularization in patients with coronary artery disease and ventricular tachycardia or fibrillation in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry
- Creators
- James Cook - Springfield, Mass, and Seattle, WashCarlos Rizo-Patron - Springfield, Mass, and Seattle, WashAnne Curtis - Springfield, Mass, and Seattle, WashAnne Gillis - Springfield, Mass, and Seattle, WashJThomas BiggerSteven Kutalek - Springfield, Mass, and Seattle, WashJames Coromilas - Springfield, Mass, and Seattle, WashBradley Hofer - Springfield, Mass, and Seattle, WashJudy Powell - Springfield, Mass, and Seattle, WashAlfred Hallstrom - Springfield, Mass, and Seattle, Washfor the AVID Investigators
- Publication Details
- The American heart journal, v 143(5), pp 821-826
- Publisher
- Elsevier Limited
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000176063800012
- Scopus ID
- 2-s2.0-0036271821
- Other Identifier
- 991019340590204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems