Journal article
Effective Doses of Low-Dose Naltrexone for Chronic Pain – An Observational Study
Journal of pain research, v 17, pp 1273-1284
2024
PMID: 38532991
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Low-dose naltrexone (LDN) has been used to treat chronic pain. There is, however, no agreed on effective dose, leaving clinicians without guidelines on initiating treatment with naltrexone. It appears that the dose of LDN for any patient is idiosyncratic, and in a small study, ranges from 0.1 to 6.0 mg/day. Understanding the various possible mechanisms of action of LDN may help the clinician to understand how and why it can effectively reduce chronic pain. A titration schedule to establish the maximally effective dose for chronic myofascial pain is presented.
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Details
- Title
- Effective Doses of Low-Dose Naltrexone for Chronic Pain – An Observational Study
- Creators
- Norman J Marcus - Cornell CollegeLexi Robbins - MarcusAya Araki - MarcusEdward J Gracely - Drexel UniversityTheoharis C Theoharides - Tufts University
- Publication Details
- Journal of pain research, v 17, pp 1273-1284
- Publisher
- Dove
- Grant note
- ;
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- MD (Doctor of Medicine) Program
- Web of Science ID
- WOS:001189099600001
- Scopus ID
- 2-s2.0-85188514373
- Other Identifier
- 991021864466404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology