Journal article
Effectiveness of Lifestyle Interventions for Individuals With Severe Obesity and Type 2 Diabetes
Diabetes care, v 34(10), pp 2152-2157
01 Oct 2011
PMID: 21836103
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
OBJECTIVE-Rates of severe obesity (BMI 40 kg/m(2)) are on the rise, and effective treatment options are needed. We examined the effect of an intensive lifestyle intervention (ILI) on weight loss, cardiovascular disease (CVD) risk, and program adherence in participants with type 2 diabetes who were severely obese compared with overweight (BMI 25 to <30 kg/m(2)), class I (BMI 30 to <35 kg/m(2)), and class II (BMI 35 to <40 kg/m(2)) obese participants.
RESEARCH DESIGN AND METHODS-Participants in the Action for Health in Diabetes (Look AHEAD) trial were randomly assigned to ILI or diabetes support and education (DSE). DSE participants received a less intense educational intervention, whereas ILI participants received an intensive behavioral treatment to increase physical activity (PA) and reduce caloric intake. This article focuses on the 2,503 ILI participants (age 58.6 +/- 6.8 years).
RESULTS-At 1 year, severely obese participants in the ILI group lost 9.04 7.6% of initial body weight, which was significantly greater (P < 0.05) than ILI participants who were overweight (-7.43 +/- 5.6%) and comparable to class I (-8.72 +/- 6.4%) and class II obese (-8.64 +/- 7.4%) participants. All BMI groups had comparable improvements in fitness, PA, LDL cholesterol, triglycerides, blood pressure, fasting glucose, and HbA(1c) at 1 year. ILI treatment session attendance was excellent and did not differ among weight categories (severe obese 80% vs. others 83%; P = 0.43).
CONCLUSIONS-Severely obese participants in the ILI group had similar adherence, percentage of weight loss, and improvement in CVD risk compared with less obese participants. Behavioral weight loss programs should be considered an effective option for this population.
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Details
- Title
- Effectiveness of Lifestyle Interventions for Individuals With Severe Obesity and Type 2 Diabetes
- Creators
- Jessica L. Unick - Miriam HospitalDaniel Beavers - Wake Forest UniversityJohn M. Jakicic - University of PittsburghAbbas E. Kitabchi - University of Tennessee at KnoxvilleWilliam C. Knowler - Phoenix (United States)Thomas A. Wadden - College Station Medical CenterRena R. Wing - Miriam (Norway)Look AHEAD Res GrpEllen Stephanie Krauthamer Ewing - Drexel University
- Publication Details
- Diabetes care, v 34(10), pp 2152-2157
- Publisher
- Amer Diabetes Assoc
- Number of pages
- 6
- Grant note
- DK-57136; DK-57149; DK-56990; DK-57177; DK-57171; DK-57151; DK-57182; DK-57131; DK-57002; DK-57078; DK-57154; DK-57178; DK-57219; DK-57008; DK-57135; DK-56992 / Department of Health and Human Services, National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA U01DK057178 / NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) DK-046204 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA M01RR01066 / Massachusetts General Hospital Mallinckrodt General Clinical Research Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) M01RR000056 / NATIONAL CENTER FOR RESEARCH RESOURCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) Google; Google Incorporated P60DK079637 / Johns Hopkins-University of Maryland Diabetes Research and Training Center M01RR00051 / University of Colorado Health Sciences Center General Clinical Research Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) University of Washington/VA Puget Sound Health Care System Medical Research Service, Department of Veterans Affairs; University of Washington; US Department of Veterans Affairs M01RR01346 / Frederic C. Banter General Clinical Research Center M01RR0021140 / University of Tennessee at Memphis General Clinical Research Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) M01RR02719 / The Johns Hopkins Medical Institutions Bayview General Clinical Research Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) P30 DK48520 / Clinical Nutrition Research Unit National Institute of Diabetes and Digestive and Kidney Diseases; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) M01RR000056 44 / University of Pittsburgh General Clinical Research Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) BodyMedia, Inc.
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Counseling and Family Therapy; Drexel University
- Web of Science ID
- WOS:000301609000003
- Scopus ID
- 2-s2.0-83055166908
- Other Identifier
- 991020100197404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Endocrinology & Metabolism