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Effects of Particle Size of Inhaled Corticosteroid on the Voice
Journal article

Effects of Particle Size of Inhaled Corticosteroid on the Voice

Dylan Vance, Ghiath Alnouri, William Valentino, Daniel Eichorn, Pankti Acharya and Robert T. Sataloff
Journal of voice, v 35(3), pp 455-457
May 2021
DOI: https://doi.org/10.1016/j.jvoice.2019.11.013
PMID: 31902681
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Asthma Complications Inhaler Particle size Small Standard Vocalis muscle atrophy
The purpose of this study was to determine if inhaled corticosteroid (ICS) particle size influences the development of laryngitis including candida laryngitis, dysphonia, or vocalis muscle atrophy in asthmatic patients. Retrospective analysis. Medical records of patients from a quaternary care laryngology practice who have asthma were reviewed retrospectively. Subjects were divided into two groups determined by the particle size of their ICS, small or standard. Each patient only used one type of inhaler. All subjects had been seen in the office for dysphonia evaluation. Statistical analysis was performed on the collected data using χ2 analysis with Yate's Correction for categorical data and a student t-test for means. A P value of less than 0.05 was considered significant. There was a significant difference in vocal fold atrophy rate between groups. Routine use of standard particle size ICS is associated with more atrophy than small size ICS.

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6 citations in Web of Science
9 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Audiology & Speech-language Pathology
Otorhinolaryngology
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