Journal article
Effects of a Low-intensity Intervention That Prescribed a Low-carbohydrate vs. a Low-fat Diet in Obese, Diabetic Participants
Obesity (Silver Spring, Md.), v 18(9), pp 1733-1738
Sep 2010
PMID: 20019677
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Low-carbohydrate diets have been associated with significant reductions in weight and HbA(1c) in obese, diabetic participants who received high-intensity lifestyle modification for 6 or 12 months. This investigation sought to determine whether comparable results to those of short-term, intensive interventions could be achieved over a 24-month study period using a low-intensity intervention that approximates what is feasible in outpatient practice. A total of 144 obese, diabetic participants were randomly assigned to a low-carbohydrate diet (<30 g/day) or to a low-fat diet (<= 30% of calories from fat with a deficit of 500 kcal/day). Participants were provided weekly group nutrition education sessions for the first month, and monthly sessions thereafter through the end of 24 months. Weight, HbA(1c), glucose, and lipids were measured at baseline and 6, 12, and 24 months. Of the 144 enrolled participants, 68 returned for the month 24 assessment visit. Weights were retrieved from electronic medical records for an additional 57 participants (total, 125 participants) at month 24. All participants with a baseline measurement and at least one of the three other measurements were included in the mixed-model analyses (n = 138). The low-intensity intervention resulted in modest weight loss in both groups at month 24. At this time, participants in the low-carbohydrate group lost 1.5 kg, compared to 0.2 kg in the low-fat group (P = 0.147). Lipids, glycemic indexes, and dietary intake did not differ between groups at month 24 (or at months 6 or 12)
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Details
- Title
- Effects of a Low-intensity Intervention That Prescribed a Low-carbohydrate vs. a Low-fat Diet in Obese, Diabetic Participants
- Creators
- Nayyar Iqbal - Hospital of the University of PennsylvaniaMarion L. Vetter - University of PennsylvaniaRenee H. Moore - University of PennsylvaniaJesse L. Chittams - University of PennsylvaniaCornelia V. Dalton-Bakes - Hospital of the University of PennsylvaniaMonique Dowd - Mercy Hospital SpringfieldCatherine Williams-Smith - University of PennsylvaniaSerena Cardillo - Hospital of the University of PennsylvaniaThomas A. Wadden - University of Pennsylvania
- Publication Details
- Obesity (Silver Spring, Md.), v 18(9), pp 1733-1738
- Publisher
- Wiley
- Number of pages
- 6
- Grant note
- VA Merit Review Entry Program; US Department of Veterans Affairs
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000281512400009
- Scopus ID
- 2-s2.0-77956094223
- Other Identifier
- 991021448055804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Endocrinology & Metabolism
- Nutrition & Dietetics