Journal article
Effects of aging at the adrenergic cardiac neuroeffector junction
Federation proceedings, v 45(1), pp 45-47
01 Jan 1986
PMID: 3940907
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Adrenergic neural degeneration was seen to increase with age. This is thought to contribute to the decreased cardiac content of the transmitter. Pharmacologically, it was found with the use of tyramine that virtually all of the norepinephrine (NE) pool is available for release, and that there is no difference in the amount of NE released in relation to age. Cardiac responsiveness to adrenergic agonists decreases with age. Our results suggest that this is caused in great measure by increased activity of the prejunctional, neuronal uptake mechanism in the older animal.
Metrics
6 Record Views
Details
- Title
- Effects of aging at the adrenergic cardiac neuroeffector junction
- Creators
- P B GoldbergM S KreiderM R McLeanJ Roberts
- Publication Details
- Federation proceedings, v 45(1), pp 45-47
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Emergency Medicine
- Web of Science ID
- WOS:A1986AXT4000009
- Scopus ID
- 2-s2.0-0022551010
- Other Identifier
- 991019184031604721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biology