Journal article
Effects of cortical activation on sensory responses in barrel cortex
Journal of neurophysiology, v 105(4), pp 1495-1505
Apr 2011
PMID: 21273311
Abstract
Neocortex network activity changes from a deactivated state during quiescence to an activated state during arousal and vigilance. In urethane-anesthetized rats, cortical activation is readily produced by either stimulating the brainstem reticular formation or by application of cholinergic agonists into the thalamus. We studied the effects of cortical activation on spontaneous activity and sensory responses in the barrel cortex. Cortical activation leads to a suppression of low-frequency sensory responses and to a reduction in their variability due to the abolishment of up and down membrane potential fluctuations in cortical cells. Overall, sensory responses become sharper and more reliable during cortical activation.
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Details
- Title
- Effects of cortical activation on sensory responses in barrel cortex
- Creators
- Akio Hirata - Department of Neurobiology and Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USAManuel A Castro-Alamancos
- Publication Details
- Journal of neurophysiology, v 105(4), pp 1495-1505
- Publisher
- American Physiological Society (APS); United States
- Grant note
- R01 NS059882 / NINDS NIH HHS R35 NS097272 / NINDS NIH HHS R01 NS059036 / NINDS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000289620500007
- Scopus ID
- 2-s2.0-79955156319
- Other Identifier
- 991014877909404721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Neurosciences
- Physiology