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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Effects of prenatal cocaine exposure on pubertal development
Neurotoxicology and teratology, v 47
01 Jan 2015
PMID: 25446013
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The purpose of the current study was to examine the relationship between prenatal cocaine exposure (PCE) and pubertal development. Children (n = 192; 41% with PCE) completed the Pubertal Development Scale (Petersen et al. 1988) and provided salivary dehydroepiandrosterone (DHEA) samples at 6 month intervals from 11 to 13 years. PCE was examined as a predictor of pubertal status, pubertal tempo, and DHEA levels in mixed models analyses controlling for age, sex, environmental risk, neonatal medical problems, other prenatal exposures, and BMI. PCE interacted with age such that PCE predicted slower pubertal tempo during early adolescence. PCE also interacted with age to predict slower increases in DHEA levels during early adolescence. These findings suggest that PCE may affect pubertal development and, if slower pubertal tempo continues, could lead to delayed pubertal status in mid-adolescence. (C) 2014 Elsevier Inc. All rights reserved.
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Details
- Title
- Effects of prenatal cocaine exposure on pubertal development
- Creators
- David S. Bennett - Drexel UniversityJennifer M. Birnkrant - Rutgers Robert Wood Johnson Medical School, Institute for the Study of Child Development, 89 French Street, New Brunswick, NJ 08901, United StatesDennis P. Carmody - Rutgers Robert Wood Johnson Medical School, Institute for the Study of Child Development, 89 French Street, New Brunswick, NJ 08901, United StatesMichael Lewis - Rutgers Robert Wood Johnson Medical School, Institute for the Study of Child Development, 89 French Street, New Brunswick, NJ 08901, United States
- Publication Details
- Neurotoxicology and teratology, v 47
- Publisher
- Elsevier
- Number of pages
- 8
- Grant note
- R01DA007109 / NATIONAL INSTITUTE ON DRUG ABUSE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA); European Commission R01 DA007109 / National Institute on Drug Abuse; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA); European Commission
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychiatry
- Web of Science ID
- WOS:000348955000016
- Scopus ID
- 2-s2.0-84922368923
- Other Identifier
- 991019169913704721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Neurosciences
- Toxicology