Journal article
Electrode potential, inflammatory solution chemistry and temperature alter Ti-6Al-4V oxide film properties
Electrochimica acta, v 462, 142770
10 Sep 2023
Abstract
Post implantation, a thin TiO2 film protects Ti-6Al-4V in vivo. Mechanically and chemically destructive conditions may disrupt this oxide film and promote corrosion at the device interface. While tribocorrosion has been explored in vitro, pre-clinical tests fail to fully reproduce the damage documented on retrievals. A gap persists in our fundamental knowledge of the oxide film and its response to adverse electrochemical events. In this study, we first characterized the TiO2 oxide film structure after inducing & beta; phase selective dissolution. Next, we used electrochemical impedance spectroscopy and Mott-Schottky analysis to investigate the oxide film on freshly prepared surfaces following negative potential excursions. We systematically increased electrode potential from -1 V vs. Ag/AgCl in 0.1 V steps to +0.5 V. Various H2O2 concentrations (0.1 M to 0.001 M) in phosphate buffered saline and temperatures ranging from 24 degrees C to 55 degrees C were investigated. Atomic force microscopy showed morphological changes to oxide domes over the & alpha; phase following & beta; phase selective dissolution. Below the Ti-6Al4V open circuit potential (ca. -0.3 V), we identified systematic variations in polarization resistance (Rp) and capacitance (C) with potential, solution chemistry, and temperature. The combined effect of cathodic activation and H2O2 solution concentration synergistically and systematically decreased Rp by orders of magnitude (p = 0.000). Increased solution temperatures decreased Rp (p = 0.000). At high concentrations of ROS (0.1 M), we documented changes in constant phase element capacitance, from n-type to p-type. Finally, we developed empirical equations to predict Rp for a given concentration, temperature, and potential. In totality, these experiments help to further elucidate the complex interactions at the oxide-biology interface in vivo and provide guidance for in vitro testing methods development.
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Details
- Title
- Electrode potential, inflammatory solution chemistry and temperature alter Ti-6Al-4V oxide film properties
- Creators
- Michael A. Kurtz - Clemson UniversityAudrey C. Wessinger - Clemson UniversityLilliana M. Taylor - Medical University of South CarolinaJeremy L. Gilbert - Clemson University
- Publication Details
- Electrochimica acta, v 462, 142770
- Publisher
- Elsevier
- Number of pages
- 13
- Grant note
- DePuy Synthes Wyss Endowment at Clemson University
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:001037279900001
- Scopus ID
- 2-s2.0-85163559087
- Other Identifier
- 991022038960004721
InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Electrochemistry