Journal article
Electrolyte Intake and Nonpharmacologic Blood Pressure Control
Annals of epidemiology, v 12(8), pp 587-595
2002
PMID: 12495832
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
PURPOSE: To characterize relationships between sodium and potassium intakes and blood pressure control.
METHODS: We analyzed repeated 24-hour diet recalls and 24-hour urine assays from 873 elderly participants with established hypertension in a 3-year clinical trial of lifestyle interventions. Pooled estimates of electrolyte intakes were developed using hierarchical measurement error models and related to nonpharmacologic blood pressure control.
RESULTS: Relative decreases in sodium and increases in potassium intakes each had graded relationships with better blood pressure control. After adjustment for measurement error, a 100 mmol/24-hour decrease in sodium intake was associated with an odds ratio of 2.93 [95% confidence interval: 1.83, 4.64] for maintaining nonpharmacologic blood pressure control throughout follow-up. A 50 mmol/24-hour increase in potassium intake was associated with an odds ratio of 2.00 [1.12, 3.55]. These relationships were independent of each other and of baseline levels of intakes. Blood pressure control was most strongly associated with sodium intake for participants with lower systolic blood pressures and longer duration of hypertension, and with potassium for those with elevated diastolic blood pressures.
CONCLUSIONS: Sodium and potassium intakes exert independent graded influences on nonpharmacologic blood pressure control. Correlated measurement error may spuriously introduce a dependency among these relationships.
Metrics
Details
- Title
- Electrolyte Intake and Nonpharmacologic Blood Pressure Control
- Creators
- Mark A Espeland - Wake Forest UniversityShiriki Kumanyika - University of PennsylvaniaCarla Yunis - Wake Forest UniversityBeiyao Zheng - Wake Forest UniversityW.Mark Brown - Wake Forest UniversitySharon Jackson - Wake Forest UniversityAlan C Wilson - Johnson UniversityJudy Bahnson - Wake Forest University
- Publication Details
- Annals of epidemiology, v 12(8), pp 587-595
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Dana and David Dornsife School of Public Health
- Web of Science ID
- WOS:000179471300007
- Scopus ID
- 2-s2.0-0036862943
- Other Identifier
- 991019312328204721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health